Epilepsy Research and Resources

Neurosurgery One is committed to providing all patients with evidence-based medical treatments. Information on our epilepsy pages comes from the studies listed below.

• Englot DJ, Ouyang D, Garcia PA, Barbaro NM, Chang EF. Epilepsy surgery trends in the United States, 1990-2008. Neurology. 2012;78(16):1200-1206. https://doi.org/10.1212/WNL.0b013e318250d7ea
• Engel J Jr, McDermott MP, Wiebe S, et al. Early surgical therapy for drug-resistant temporal lobe epilepsy: a randomized trial. The Journal of American Medical Association. 2012 Mar 7;307(9):922-30. https://doi.org/10.1001/jama.2012.220
• Simasathien T, Vadera S, Najm I, et al. Improved outcomes with earlier surgery for intractable frontal lobe epilepsy. Annals of Neurology. 2013 May;73(5):646-54. https://doi.org/10.1002/ana.23862
• Taft C, Sager Magnusson E, Ekstedt G, Malmgren K. Health-related quality of life, mood, and patient satisfaction after epilepsy surgery in Sweden—a prospective controlled observational study. Epilepsia. 2014;55(6):878-885. https://doi.org/10.1111/epi.12616
• Neal EG, Maciver S, Schoenberg MR, Vale FL. Surgical disconnection of epilepsy network correlates with improved outcomes. Seizure. 2020;76:56-63. https://doi.org/10.1016/j.seizure.2020.01.018
• Epilepsy Foundation. Risks and Benefits. (2020, April 2). https://www.epilepsy.com/learn/treating-seizures-and-epilepsy/surgery/risks-and-benefits
• Devinsky O, Barr WB, Vickrey BG, et al. Changes in depression and anxiety after resective surgery for epilepsy. Neurology. 2005 Dec 13;65(11):1744-9. https://doi.org/10.1212/01.wnl.0000187114.71524.c
• Zarroli K, Tracy JI, Nei M, et al. Employment after anterior temporal lobectomy. Epilepsia. 2011 May;52(5):925-31. https://doi.org/10.1111/j.1528-1167.2011.03098.x
• Dawkins RL, Omar NB, Agee BS, et al. Assessment of driving outcomes after epilepsy surgery. Epilepsy & Behavior. 2015 Nov;52(Pt A):25-30. https://doi.org/10.1016/j.yebeh.2015.08.035
• Schiltz NK, Kaiboriboon K, Koroukian SM, et al. Long-term reduction of health care costs and utilization after epilepsy surgery. Epilepsia. 2016 Feb;57(2):316-24. https://doi.org/10.1111/epi.13280
• Engel J, Jr., Wiebe S, French J, et al. Practice parameter: temporal lobe and localized neocortical resections for epilepsy: Report of the Quality Standards Subcommittee of the American Academy of Neurology, in association with the American Epilepsy Society and the American Association of Neurological Surgeons. Neurology. 2003;60(4):538-547. https://doi.org/10.1046/j.1528-1157.2003.48202.x
• Wiebe S, Blume WT, Girvin JP, Eliasziw M, et al. Effectiveness, Efficiency of Surgery for Temporal Lobe Epilepsy Study G. A randomized, controlled trial of surgery for temporal-lobe epilepsy. New England Journal of Medicine. 2001;345(5):311-318. https://doi.org/10.1056/NEJM200108023450501
• Kang JY, Wu C, Tracy J, et al. Laser interstitial thermal therapy for medically intractable mesial temporal lobe epilepsy. Epilepsia. 2016 Feb;57(2):325-34. https://doi.org/10.1111/epi.13284
• Bergey, GK, Morrell, MJ, Mizrahi, EM, et al. Long-term Treatment With Responsive Brain Stimulation in Adults With Refractory Partial Seizures. Neurology. 2015;84(8):810-7. https://doi.org/10.1212/wnl.0000000000001280
• Englot DJ, Rolston JD, Wright CW, Hassnain KH, Change EF. Rates and Predictions of Seizure Freedom with Vagus Nerve Stimulation for Intractable Epilepsy. Neurology. 2016;79(3):345-353. https://doi.org/10.1227/NEU.0000000000001165